Endocrine Abstracts

Transgender patients are treated by down-regulation oft he pituitary gland and the gonads with GnRH- analogues and the opposite male or female sex steroids, followed by gonadectomy. After gonadectomy, the GnRH analogue is discontinued while the treatment with sex steroids (estrogen or testosterone) is continued. This offers the unique possibility to study the effects of sex steroids on bone density, metabolism, and other regulatory systems in the opposite sex. We present data ...